概述| 货号 | BAF303 |
| 别名 | CNTFR |
全称 | Ciliary Neurotrophic Factor Receptor alpha | | 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL)
|
| 目标/特异性 | Detects human CNTF R alpha in Western blots. In Western blots (under non-reducing and reducing conditions), greater than 50% cross‑reactivity with recombinant rat CNTF sR alpha is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL
|
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1271 (Human); 313173 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CNTF R alpha |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | The high-affinity CNTF receptor complex, which mediates the biological action of CNTF, contains the ligand-binding alpha subunit (CNTF R alpha) and two signal-transducing proteins, LIF R beta and gp130. Whereas LIF R beta and gp130 are widely expressed in many cell types, the expression of CNTF R alpha is restricted to the central and peripheral nervous systems. cDNAs encoding CNTF R alpha isolated from both human and rat share 96% amino acid sequence identity. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - CLF:CLC Complex: A Second Ligand for the CNTF Receptor
- Diabetes
- ICC / IHC Images: CNTF R alpha
- IL-6 Family
- Receptors in the Jak/STAT Pathway
- VPS10P-domain Family
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