货号 | BAF2945 |
别名 | D14S46Eneural retina-specific leucine zipper protein; neural retina leucine zipper; NRL-MAF; RP27; RP27neural retinal-specific leucine zipper | 全称 | Neural Retina-specific Leucine Zipper Protein |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human NRL in Western blots. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 4901 (Human) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness | |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human NRL Met1-Leu237 Accession # P54845 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | NRL is a nuclear transcription factor that belongs to the Maf subfamily within the bZIP (basic motif-leucine zipper) transcription factor family. It contains an N-terminal transcriptional activation domain and a C-terminal DNA-binding bZIP domain that is also involved in homo- or heterodimerization. NRL is expressed specifically in rod photoreceptors and regulates the expression of rod-specific genes. NRL is phosphorylated at multiple sites. Mutations in NRL are associated with autosomal dominant retinitis pigmentosa. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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