| 货号 | BAF2940 |
| 别名 | anthrax toxin receptor 2; ANTXR2; Capillary morphogenesis gene 2 protein; capillary morphogenesis protein 2; cI-35; CMG2MGC111533; CMG-2MGC45856; FLJ31074; ISH; JHF; JHS | 全称 | Capillary Morphogenesis Protein 2 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
| 目标/特异性 | Detects CMG‑2/ANTXR2 in Western blots. In Western blots, approximately 20% cross-reactivity with recombinant mouse CMG-2 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/106cells |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 118429 (Human); 71914 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human CMG‑2/ANTXR2 isoform 1 Gln34-Asn317 Accession # P58335 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | CMG-2 is an anthrax toxin receptor (ATR) family protein that contains one von Willebrand factor type A domain. As a result of alternative splicing, at least four isoforms of secreted or type I membrane proteins exist. CMG-2 is widely expressed in human tissues. It binds selectively to collagen type IV and laminin and is also capable of binding the protective antigen (PA) of Bacillus anthracis in a divalent cation-dependent manner. Soluble CMG-2 is a potent antitoxin and may be used as a treatment for anthrax. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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Detection of CMG‑2/ANTXR2 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Goat Anti-Human CMG‑2/ANTXR2 Biotinylated Antigen Affinity‑purified Polyclonal Antibody (Catalog # BAF2940, filled histogram) or isotype control antibody (Catalog # BAF108, open histogram), followed by Streptavidin-Phycoerythrin (Catalog # F0040). |
