| 货号 | BAF2796 |
| 别名 | corticotropin releasing hormone binding protein; corticotropin-releasing factor-binding protein; Corticotropin-releasing hormone-binding protein; CRFBP; CRFBPcorticotropin releasing hormone-binding protein; CRF-BPCRF-binding protein; CRH-BP | 全称 | Corticotropin Releasing Hormone Binding Protein |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human CRHBP in Western blots. In Western blots, approximately 40% cross-reactivity with recombinant human CRHBP is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1393 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human CRHBP Tyr25-Leu322 Accession # P24387.2 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | CRHBP (Corticotrophin-releasing Hormone-Binding Protein) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds. Species differences exist; human CRHBP is found in plasma while rodent and sheep CRHBP is limited to neuroendocrine tissues. CRHBP is presumed to either sequester CRH, rendering it unavailable to cells or transport it to target tissues. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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