| 货号 | BAF2537 |
| 别名 | GLC1A; GLC1Amyocilin; GPOA; JOAG; JOAG1; MYOC; myocilin, trabecular meshwork inducible glucocorticoid response; TIGR; TIGRmutated trabecular meshwork-induced glucocorticoid response protein; Trabecular meshwork-induced glucocorticoid response protein |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Myocilin in Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4653 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Myocilin Arg33-Met504 Accession # Q99972 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Myocilin (also known as TIGR) is a variably glycosylated, 65 kDa,secreted polypeptide that belongs to the family of olfactomedin-relatedproteins. Human Myocilin is synthesized as a 490 amino acid (aa)precursor that contains an 18 aa signal sequence, an 84 aa N-terminus,a 53 aa alpha -helical leucine zipper and a 335 aa C-terminus that containsa 260 aa OLF-domain. An alternate start site generates asignal-sequenceless 504 aa mature protein. Myocilin formsnondisulfide-linked dimers and multimers. The human 32 kDa OLF-domainshares 87% aa sequence identity with the OLF-domain in bovine, rat andmouse. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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