货号 | BAF2366 |
别名 | ECSM4; FLJ20798; Magic roundabout; MGC133352; MGC133353; MRB; roundabout homolog 4; roundabout homolog 4, magic roundabout (Drosophila) | 全称 | Roundabout Homolog 4 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
目标/特异性 | Detects human ROBO4 in Western blots. In Western blots, less than 2% cross-reactivity with recombinant rat ROBO1 is observed. |
使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 54538 (Human); 74144 (Mouse) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis. | |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human ROBO4 Gln28-Arg467 Accession # Q8WZ75 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Members of the ROBO family are a group of highly conserved transmembrane glycoproteins that make up a small subgroup of the immunoglobulin (Ig) superfamily. They are characterized structurally by five C2-type Ig-like repeats, three fibronectin type III domains, a transmembrane region, and an intracellular domain with three (ROBO3) or four (ROBO1, 2) CC (conserved cytoplasmic) motifs. ROBO4, a fourth putative family member, has been identified, but lacks one of the three fibronectin-like domains and two of the five Ig-like domains. ROBOs are best known for their roles as receptors for the Slit family of repellent axon guidance cues. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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