货号 | BAF2304 |
别名 | Cerebroglycan; GPC2 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human Glypican 2 in Western blots. In Western blots, approximately 45% cross-reactivity with recombinant mouse Glypican 2 is observed and less than 2% cross-reactivity with recombinant human (rh) Glypican 3, rhGlypican 5, and rhGlypican 6 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 221914 (Human); 71951 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human Glypican 2 Pro18-Ser553 Accession # Q8N158 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The glypicans (GPC) constitute a family of glycosylphosphatidylinositol (GPI)-anchored, heparan sulfate proteoglycans. Six members of this family have been identified in mammals (GPC1-GPC6). All glypican core proteins contain an N-terminal signal peptide, a large globular cysteine-rich domain (CRD) with 14 invariant cysteine residues, a stalk-like region containing the heparan sulfate attachment sites, and a C-terminal GPI attachment site. Glypican 2, also known as cerebroglycan, binds Midkine and is primarily expressed in developing neuronal tissues. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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