货号 | BAF2246 |
别名 | FGF-12; FGF12B; FHF1; FHF-1; FHF1Fibroblast growth factor homologous factor 1; fibroblast growth factor 12; fibroblast growth factor 12B; fibroblast growth factor FGF-12b; Myocyte-activating factor | 全称 | Fibroblast Growth Factor 12 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human FGF-12 in Western blots. In Western blots, approximately 30% cross‑reactivity with recombinant human (rh) FGF-13B is observed, 15% cross-reactivity with rhFGF-11 is observed and less than 1% cross-reactivity with rhFGF-3, rhFGF-4, rhFGF-6, rhFGF-7, recombinant mouse (rm) FGF-8b, rhFGF-9, rhFGF-10, rmFGF-15, rhFGF-16, rhFGF-17, rhFGF-18, rhFGF-19, rhFGF-20, rhFGF-23, rhFGF acidic, and rhFGF basic is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 2257 (Human) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human FGF-12 Glu67-Thr243 Accession # P61328 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | FGF-12 is a member of the FGF superfamily of heparin-binding mitogenic molecules characterized by the presence of a core, 120 amino acid (aa) beta-trefoil structure. FGF-11, -12, -13, -14, originally termed FGF homologous factors (FHF) -3, -1, -2, and -4, respectively, form a subgroup within the FGF family. Human FGF-12/FHF-1 is synthesized as a 243 aa protein. It lacks a typical signal sequence and is considered cytoplasmic. It also possess an N-terminal bipartite nuclear localization signal at aa 11-18 and 28-38. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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