| 货号 | BAF2097 |
| 别名 | DPC4; DPC4SMAD, mothers against DPP homolog 4 (Drosophila); hSMAD4; JIP; MAD homolog 4; MADH4; MADH4mothers against decapentaplegic homolog 4; mothers against decapentaplegic homolog 4; mothers against decapentaplegic, Drosophila, homolog of, 4; SMAD 4; SMAD family member 4MAD, mothers against decapentaplegic homolog 4 (Drosophila); SMAD, mothers against DPP homolog 4; Smad4 | 全称 | Mothers Against DPP Homolog 4 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Smad4 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human (rh) Smad1 is observed and less than 2% cross-reactivity with rhSmad5, rhSmad7, and rhSmad9 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 4089 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human Smad4 Pro139-Asp332 Accession # Q13485 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Smads are a family of intracellular proteins that transmit transforminggrowth factor beta (TGF-beta ) superfamily signals from the cell surface tothe nucleus. Upon signal-induced phosphorylation, Smad subunitsassociate with the common-mediator subunit, Smad4. This heteromericcomplex then translocates into the nucleus to exert transcriptionalcomodulator activity. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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