| 货号 | BAF2049 |
| 别名 | BXMH1; CD307a antigen; CD307a; Fc receptor homolog 1; Fc receptor-like 1; FcRH1; FCRH1DKFZp667O1421; FcRL1; FcR-like protein 1; hIFGP1; IFGP family protein 1; IFGP1; IFGP1Fc receptor-like protein 1; Immune receptor translocation-associated protein 5; IRTA5; IRTA5immunoglobulin superfamily Fc receptor, gp42 | 全称 | Fc Receptor-like 1 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human FCRL1/FcRH1 in Western blots. In Western blots, approximately 25% cross‑reactivity with recombinant human (rh) IRTA4 is observed and less than 5% cross-reactivity with rhIRTA1, rhIRTA2 and rhIRTA3 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 115350 (Human); 229499 (Mouse); 680665 (Rat) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human FCRL1/FcRH1 Ala17-His304 Accession # Q96LA6 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Fc receptor homologs, also known as IRTA or IFGP (IgSF, FcR, gp42) proteins, are transmembrane proteins with sequence homology to classical Fc receptors. FcRH have from three to nine Ig-like domains in their extracellular region and variable combinations of cytoplasmic immunotyrosine activation or inhibitory motifs (ITAM or ITIM). FcRH function as activating or inhibitory receptors on discrete B cell populations and are involved in lymphocyte development and transformation. No ligands for these proteins have been identified. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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