| 货号 | BAF1956 |
| 别名 | BMP binding endothelial regulator; BMP-binding endothelial regulator precursor protein; BMP-binding endothelial regulator protein; BMPER; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator; CRIM3; crossveinless 2; crossveinless-2; CV2; CV-2; hCV2; KIAA1965; Protein crossveinless-2 | 全称 | BMP-binding Endothelial Regulator Protein |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Crossveinless‑2/CV‑2 in Western blots. In Western blots, approximately 15% cross-reactivity with recombinant mouse CV-2 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 168667 (Human); 73230 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Crossveinless‑2/CV‑2 Val34-Arg685 Accession # Q8N8U9 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Crossveinless-2 (CV-2), also known as bone morphogenetic protein-binding endothelial cell precursor-derived regulator (BMPER), is a secreted Chordin-like protein that modulates the BMP signaling pathway. Human CV-2 is synthesized as a 685 amino acid (aa) precursor protein with a putative 39 aa signal peptide, five tandem Chordin-like, cysteine-rich domains, a partial von Willebrand factor type D domain (vWD), and a carboxy terminal-trypsin inhibitor-like cysteine-rich domain (TIL). Secreted CV-2 is reported to be proteolytically cleaved to generate two fragments that are disulfide-linked. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|