货号 | BAF1907 |
别名 | B Lymphocyte Activator Macrophage Expressed; BCM-Like Membrane Protein; B-Lymphocyte Activator Macrophage Expressed; CD353 Antigen; CD353; SBBI42; SLAM Family Member 8; SLAMF8 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
目标/特异性 | Detects human BLAME/SLAMF8 in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human NTB-A/SLAMF6 is observed. |
使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 56833 (Human) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human BLAME/SLAMF8 Ala23-Asp233 Accession # Q9P0V8 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | BLAME, also known as Signaling Lymphocyte Activation Molecule Family Member 8 (SLAMF8), is an Ig superfamily protein that is a member of the SLAM/CD150/CD2 family of receptors. It is expressed on macrophages and dendritic cells. BLAME modulates signaling through the B cell receptor and may also function during B lineage commitment. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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Detection of BLAME/SLAMF8 in U937 Human Cell Line by Flow Cytometry. U937 human histiocytic lymphoma cell line was treated for 18 hours with 20 ng/mL Recombinant Human IFN‑ gamma (Catalog # 285-IF) then stained with Human BLAME/SLAMF8 Biotinylated Antigen Affinity-purified Polyclonal Antibody (Catalog # BAF1907, filled histogram) or isotype control antibody (Catalog # BAF108, open histogram), followed by Streptavidin-Phycoerythrin (Catalog # F0040). |