货号 | BAF1748 |
别名 | CD367; CLEC4A; CLECSF6; CLECSF6C-type lectin superfamily member 6; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 6; C-type lectin domain family 4 member A; C-type lectin domain family 4, member A; DCIRLLIR; DDB27; DDB27C-type lectin DDB27; Dendritic cell immunoreceptor; Lectin-like immunoreceptor; LLIR | 全称 | Dendritic Cell Immunoreceptor |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Flow Cytometry(2.5 µg/106cells) |
目标/特异性 | Detects human DCIR/CLEC4A in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 2.5 µg/106cells |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 50856 (Human); 26888 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human DCIR/CLEC4A isoform 1 Gln70-Leu237 Accession # Q9UMR7 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | DCIR, also known as lectin-like immunoreceptor (LLIR), is a type II transmembrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. DCIR is expressed on dendritic cells, B cells, monocytes/macrophages and granulocytes. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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