货号 | BAF1396 |
别名 | Alpha-2-thiol proteinase inhibitor; BDK; bradykinin; Fitzgerald factor; High molecular weight kininogen; kininogen 1; kininogen; kininogen-1; KNGHMWK; Williams-Fitzgerald-Flaujeac factor |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human Kininogen/Kininostatin in Western blots. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 3827 (Human); 16644 (Mouse); 24903 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human Kininogen/Kininostatin Lys438-Ser531 Accession # P01042 |
生物活性 | Human |
标记 | Biotin |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Kininogen, also known as 2-thiol proteinase inhibitor, is a multi-functional protein. The high molecule weight (HMW) form of kininogen is synthesized as a precursor protein (amino acid residues 1 to 644). The mature chain (residues 19 to 644) is further processed into the heavy chain (residues 19 to 380) and the light chain (residues 390 to 644) with release of the active peptide bradykinin. The heavy chain consists of three cystatin-like domains, which inhibit cysteine proteases. The light chain consists of a His-rich domain, which is associated with clotting activity. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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