| 货号 | BAF2170 |
| 别名 | bB379O24.1; GATA binding factor-5; GATA binding protein 5; GATA-binding factor 5; GATA-binding protein 5; transcription factor GATA-5 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human GATA-5 in Western blots. In Western blots, less than 2% cross-reactivity with recombinant human (rh) GATA-1, rhGATA-2, rhGATA-3, rhGATA-4 and rhGATA-6 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 140628 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human GATA-5 Met1-Ala397 Accession # Q9BWX5 |
| 生物活性 | Human |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | GATA proteins are transcriptional coactivators with two GATA-type zinc fingers. GATAs bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. GATA-1, -2, -3 are selectively expressed in hematopoietic and endothelial cells, while GATA-4, -5, and -6 are expressed in developing heart and gut-derived tissues. GATA-1 and -3 exist in multiple alternatively spliced isoforms. GATA-5 is important in the development and differentiation of endoderm-derived organs, including heart and gastrointestinal tissues. GATA-5 has also been implicated in cancer development. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|