Dopa Decarboxylase/DDC Affinity Purified Polyclonal Ab (100 UL)
货号：
PPS065 基本售价：
5373.6 元 规格：
-
产品信息
概述| 货号 | PPS065 |
| 别名 | AADC; AADCaromatic-L-amino-acid decarboxylase; DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); DOPA decarboxylase; EC 4.1.1; EC 4.1.1.28 |
| 应用 | Western Blot(1:1000 dilution)
|
| 目标/特异性 | Human, bovine, canine, guinea pig, rabbit, rat, and sheep ~55 kDa DOPA Decarboxylase (DDC) in Western blots. |
| 使用方法 | Western Blot: 1:1000 dilution
|
| 来源 | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1644 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Dopa Decarboxylase/DDC |
| 生物活性 | Human, Rat, Bovine, Canine, Guinea Pig, Rabbit, Sheep |
| 标记 | Unconjugated |
| 背景 | DOPA decarboxylase (Aromatic-L-amino acid decarboxylase; also DDC) is a 54 kDa member of the alpha -family of pyroxidal phosphate enzymes. Functional DDC is a homodimeric, pyridoxal phosphate-dependent enzyme that calatyzes the decarboxylation of DOPA to dopamine, L-tryptophan to tryptamine, and 5-hydroxytryptophan to serotonin. Both dopamine and serotonin are important neurotransmitters. It also demonstrates deaminase activity, and is regulated by O2 availability. Bovine DDC is 487 amino acids (aa) in length and contains an N-terminal decarboxylase domain (aa 35-414) and a C-terminal pyroxidal binding site (L303). Bovine DDC is 88% and 86% aa identical to human and rat DDC, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 | - Kang, U.J. and T.H. Joh (1990) Brain Res. Mol. Brain Res. 8:83.
- Ichinose, H. et al. (1989) Biochem. Biophys. Res. Commun. 164:1024.
- Moore, P.S. et al. (1996) Biochem. J. 315:249.
- Bertoldi, M. and C.B. Voltattorni (2003) Biochim. Biophys. Acta 1647:42.
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参考图片Detection of Dopa Decarboxylase/DDC by Western Blot. Western blot of bovine adrenal medulla lysate showing specific immunolabeling of the ~55 kDa DDC protein. |
