| 货号 | PAF-ST4 |
| 别名 | signal transducer and activator of transcription 4; SLEB11 | 全称 | Signal Transducer and Activator of Transcription 4 |
| 反应种属 | Human/Mouse |
| 应用 | Western Blot(0.2 µg/mL) Immunoprecipitation(1 µg/106cells) |
| 目标/特异性 | Detects human and mouse STAT4. No cross-reactivity with the other STATs has been detected by immunoprecipitation or by Western blotting. |
| 使用方法 | Western Blot: 0.2 µg/mL Immunoprecipitation: 1 µg/106cells |
| 来源 | Sterile PBS to a final concentration of 0.2 mg/mL. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 6775 (Human); 20849 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Leukemia inhibitory factor is linked to regulatory transplantation tolerance. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse STAT4 synthetic peptide aa 675-749 |
| 生物活性 | Human, Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Sterile PBS to a final concentration of 0.2 mg/mL. |
| 背景 | Signal transduction and activator of transcription 4 (STAT4) is a member of the Jak/STAT signal transduction pathway. STAT4 mediates cytokine signaling by acting as a signal transducer in the cytoplasm and, upon phosphorylation, homo or heterodimerizes with other STAT proteins, which then translocate to the nucleus and activate transcription of specific genes. STAT4 is expressed in subset of tissues including spleen, heart, brain, peripheral blood cells and testis. STAT4 is involved in mediating IL-12 response in lymphocytes and regulating T helper cell differentiation. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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