货号 | AF4239 |
别名 | LILRC2 | 全称 | Leukocyte Immunoglobulin-like Receptor C2 |
反应种属 | Rat |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects rat LILRC2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant rat LILRC1 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 690906 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant rat LILRC2 Gly24-Asn230 Accession # AAY44812 |
生物活性 | Rat |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | LILRC2 (leukocyte immunoglobulin-like receptor C2) is a 35 kDa member of a family of inhibitory and stimulatory receptors (LILRs) that are expressed on hematopoietic cells. Mature rat LILRC2 is a type I transmembrane (TM) protein that is 241 amino acids (aa) in length. It contains a 207 aa extracellular domain (ECD), a 19 aa TM segment, and a short cytoplasmic tail. The ECD contains two Ig-like domains while the TM segment possesses an Arg residue. This suggests that LILRC2 is an activating receptor that may interact with Fc epsilon RI gamma and/or CD3 zeta. Cells expressing LILRC2 include neutrophils, B cells, and CD4+ and CD8+ T cells. No human or mouse LILRC2 is known. |
运输条件 | Blue Ice |
存放说明 | -20℃ |