| 货号 | AF2954 |
| 别名 | cytokine high in normal-1; Cytokine HIN-1; High in normal 1; HIN-1; HIN1Pneumo secretory protein 2; LU105; PNSP2; PnSP-2; PnSP-2Uteroglobin-related protein 2; SCGB3A1; secretoglobin family 3A member 1; secretoglobin, family 3A, member 1; UGRP2; UGRP2MGC87867 | 全称 | High in Normal 1 |
| 反应种属 | Mouse/Rat |
| 应用 | Western Blot(1 µg/mL) |
| 目标/特异性 | Detects mouse HIN‑1/SCGB3A1 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human HIN-1 is observed. |
| 使用方法 | Western Blot: 1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 92304 (Human); 73945 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. IFN-gamma down-regulates Secretoglobin 3A1 gene expression. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse HIN‑1/SCGB3A1 Phe22-Gly104 Accession # Q920D7 |
| 生物活性 | Mouse, Rat |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | HIN-1, also known as PnSP‑2, LuLeu‑2, UGRP‑2 and SCGB3A1, is an 10 kDa member of the secretoglobulin family of molecules. It is synthesized as a 104 amino acid (aa) precursor that contains a 21 aa signal sequence and an 83 aa mature region. There are no potential N‑linked glycosylation sites. Based on other members of the family, HIN‑1 is likely to exist as a disulfide‑linked homodimer. The molecule is found in mammary and upper airway epithelium. No receptor for HIN‑1 has been identified. Mature mouse HIN‑1 shares 60% aa sequence identity with mature human HIN‑1. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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Detection of Rat HIN-1 by Western Blot. Western blot shows lysates of rat lung tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Mouse/Rat HIN‑1/SCGB3A1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2954) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for HIN-1 at approximately 10 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8. |
