货号 | PAF-ST2 |
别名 | interferon alpha induced transcriptional activator; ISGF-3; MGC59816; P113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kD; signal transducer and activator of transcription 2, 113kDa; STAT113 | 全称 | Signal Transducer and Activator of Transcription 2 |
反应种属 | Human |
应用 | Immunoprecipitation(3 µg/106cells) |
使用方法 | Western Blot Immunoprecipitation: 3 µg/106cells |
来源 | Sterile PBS to a final concentration of 0.2 mg/mL. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 6773 (Human); 20847 (Mouse) |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Sterile PBS to a final concentration of 0.2 mg/mL. |
背景 | Signal transducer and activator of transcription 2 (STAT2) has an apparent M.W. of 113 kDa in SDS-PAGE gels. Human STAT2 is 851 amino acids (aa) in length and contains one SH2 domain (aa 572-667). Splicing variants produce two isoforms for human STAT2. The short isoform has a 32 aa substitution and a 199 aa deletion corresponding to aa 621 - 652 and aa 653 - 851 in the long isoform, respectively. Human STAT2 shares 73% and 65% aa sequence identity with rat and mouse STAT2, in that order. STAT2 functions as a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-α and IFN-β), and it is also required for myogenic differentiation. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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