| 货号 | AF6794 |
| 别名 | MTCP1-like protein 1; Oncogene TCL1B; Oncogene TCL-1B; SYN-1; Syncytiotrophoblast-specific protein; T-cell leukemia/lymphoma 1B; T-cell leukemia/lymphoma protein 1B; T-cell lymphoma/leukemia 1B; TCL1; TCL1/MTCP1-like protein 1; TML1; TML1TCL1/ MTCP1-like 1 | 全称 | T Cell Leukemia Protein 1B |
| 反应种属 | Human |
| 应用 | Immunohistochemistry(5-15 µg/mL) |
| 目标/特异性 | Detects human TCL1B in direct ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant human TCL1A is observed. |
| 使用方法 | Immunohistochemistry: 5-15 µg/mL |
| 来源 | Sterile PBS to a final concentration of 0.2 mg/mL. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 9623 (Human) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human TCL1B Ala2-Asp128 (Glu93Arg) Accession # O95988 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Sterile PBS to a final concentration of 0.2 mg/mL. |
| 背景 | TCL1B (T cell leukemia protein 1B; also SYN1 and [p15]TML1) is a monomeric,15 kDa (predicted) member of the TCL1 family of proteins. It is expressed in the embryo and syncytiotrophoblast, and interacts with Akt1 and Akt2 kinase, promoting their activation and the subsequent deactivation of proapoptotic molecules. Human TCL1B is 128 amino acids (aa) in length. There is no definitive structural motif that characterizes TCL1B, save for a unique beta -barrel configuration. Full length human TCL1B shares less than 35% aa identity with five orthologous mouse TCL1B isoforms. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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TCL1B in Human Lymphoma. TCL1B was detected in immersion fixed paraffin-embedded sections of human lymphoma using Goat Anti-Human TCL1B Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6794) at 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections. |
