Human/Mouse FoxF1 Affinity Purified Polyclonal Ab (100 UG)【科瑞奥博】

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Human/Mouse FoxF1 Affinity Purified Polyclonal Ab (100 UG)

货号： AF4798 基本售价： 4996.9 元规格： -

产品信息

概述
货号	AF4798
别名	FKHL5; FKHL5MGC105125; forkhead box F1; forkhead box protein F1; Forkhead, drosophila, homolog-like 5; Forkhead-related activator 1; Forkhead-related protein FKHL5; Forkhead-related transcription factor 1; FREAC-1; FREAC1ACDMPV
全称	Forkhead Box F1
反应种属	Human/Mouse
应用	Western Blot(1 µg/mL)
目标/特异性	Detects human and mouse FoxF1 in Western blots.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	2294 (Human); 15227 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21(Cip1) CDK inhibitor Oncogene, 2016;0(0):. Species: Mouse Sample Type: Cell Lysates Application: WB A Molecular atlas of Xenopus respiratory system development. Authors: Rankin S, Thi Tran H, Wlizla M, Mancini P, Shifley E, Bloor S, Han L, Vleminckx K, Wert S, Zorn A Dev Dyn, 2015;244(1):69-85. Species: Xenopus Sample Type: tissue Application: IHC Paraffin-embedded
纯化方式	Antigen Affinity-purified
免疫原	E. coli-derived recombinant human FoxF1 Met154-Met379 Accession # Q12946
生物活性	Human, Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	FoxF1 belongs to a large family of proteins that share a common forkhead/winged helix DNA binding domain. FoxF1 is implicated in pulmonary morphogenesis, specifically in development of the lung mesenchyme. Experiments in mice indicate that haploinsufficiency of FoxF1 can lead to perinatal lethality due to pulmonary abnormalities. In addition expression of FoxF1 can be induced by hedgehog ligands and appears to regulate expression of BMP-4.
运输条件	Blue Ice
存放说明	-20℃
参考文献	Cancer Stem Cell Transcription Factors Early Mesodermal Lineage Markers Forkhead Domain Transcription Factors Mesenchymal Stem Cell Transcription Factors Pluripotent Stem Cell Transcription Factors

参考图片

Detection of Human/Mouse FoxF1 by Western Blot. Western blot shows lysates of U937 human histiocytic lymphoma cell line, Jurkat human acute T cell leukemia cell line, HeLa human cervical epithelial carcinoma cell line, and NIH‑3T3 mouse embryonic fibroblast cell line. PVDF membrane was probed with 1 µg/mL of Human/Mouse FoxF1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF4798) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). A specific band was detected for FoxF1 at approximately 50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.