| 货号 | AF4630 |
| 别名 | Cadherin family member 3; CDHF3; CDHF3HT-CP; desmocollin 3; desmocollin-4; DSC; DSC1; DSC2; DSC3; DSC4; DSC4desmocollin-3; HT-CP |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human Desmocollin-3 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) Desmocollin-2 is observed and less than 1% cross-reactivity with rhDesmocollin-1 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1825 (Human); 13507 (Mouse); 307563 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human Desmocollin-3 Arg136-Lys690 Accession # Q14574 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | The transmembrane cadherin family adhesion molecule Desmocollin-3 is one of the principal components of epithelial cell desmosomes. It can be dysregulated in carcinoma and proteolytically cleaved by caspases and metalloproteases during apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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