| 货号 | AF2748 |
| 别名 | AMH; MIF; MIS; Muellerian hormone; muellerian-inhibiting factor; muellerian-inhibiting substance; Mullerian hormone; Mullerian inhibiting factor; Mullerian inhibiting substance | 全称 | Mullerian-inhibiting Substance/Anti-Mullerian Hormone |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) |
| 目标/特异性 | Detects human MIS/AMH Propeptide in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with mature recombinant human MIS is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 268 (Human); 11705 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Evidence for a Mullerian-inhibiting substance autocrine/paracrine system in adult human endometrium. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human MIS/AMH Propeptide Leu19-Gln450 Accession # P03971 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | MIS, also known as anti-Mullerian Hormone (AMH), belongs to the TGF-beta superfamily. It is synthesized as a 140 kDa homodimeric glycoprotein that undergoes proteolytic cleavage into the bioactive homodimeric 26 kDa carboxy-terminus and the 110 kDa dimeric amino-terminus. After cleavage, the amino-terminal propeptide remains non-covalently associated with the bioactive carboxy-terminal active protein. The amino acid sequence of human and mouse MIS propeptides are 67% identical. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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