| 货号 | AF2257 |
| 别名 | FGF homologous factor receptor; FGF receptor-like protein 1; FGFR5; FGFR-5; FGFRL1; FGFR-like protein; FHFR; Fibroblast growth factor receptor 5; fibroblast growth factor receptor-like 1 | 全称 | Fibroblast Growth Factor Receptor-like 1 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human FGF R5/FGFRL1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 65% cross‑reactivity with recombinant mouse (rm) FGF R5 and rmFGF R5 beta is observed and less than 1% cross-reactivity with recombinant human (rh) FGF R1 alpha (IIIb), rhFGF R1 alpha (IIIc), rhFGF R1 beta (IIIb), rhFGF R1 beta (IIIc), rhFGF R2 alpha (IIIb), rhFGF R2 alpha (IIIc), rhFGF R2 beta (IIIb), rhFGF R2 beta (IIIc), rhFGF R3 alpha (IIIb), rhFGF R3 (IIIc), and rhFGF R4 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 53834 (Human); 116701 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Rapid fusion and syncytium formation of heterologous cells upon expression of the FGFRL1 receptor. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant human FGF R5/FGFRL1 Ala25-Pro378 Accession # Q8N441 |
| 内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | FGF activity is mediated by a family of type I transmembrane tyrosine kinases, which undergo dimerization and autophosphorylation after ligand binding. Five distinct genes encode closely related FGF receptors, FGF R1 through 5. FGF Rs contain three Ig-like domains and a stretch of acidic residues between the first and second Ig-like domains. FGF R1, 2, 3, and -4 have a cytoplasmic split tyrosine-kinase domain, but FGF R5 does not. Multiple forms of FGF R1, 2, and 3 are generated by alternative splicing |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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