货号 | AF2038 |
别名 | CD43 antigen; CD43; CD43); Galactoglycoprotein; GALGP; GPL115; Leukocyte sialoglycoprotein; Leukosialin; LSN; Ly-48; sialophorin (gpL115, leukosialin, CD43); Sialophorin; SPN |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Flow Cytometry(0.25 µg/106cells) |
目标/特异性 | Detects human CD43 in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL Flow Cytometry: 0.25 µg/106cells |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 6693 (Human) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Specific and Novel microRNAs Are Regulated as Response to Fungal Infection in Human Dendritic Cells | |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human CD43 Ser20-Arg253 Accession # P16150 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | CD43 (leukosialin, sialophorin, also Ly-48 in mouse) is a type I transmembrane (TM) sialated mucin that is found on leukocytes and tumor cells. It is synthesized as a 397 amino acid (aa) precursor that contains a 19 aa signal sequence, a 234 aa extracellular region, a 23 aa TM domain, and a 123 aa cytoplasmic tail that contains an NLS. The extracellular region has 12% proline and 38% threonine and serine and shows both N- and O-linked glycosylation. Human CD43 extracellular region has less than 60% aa identity to the extracellular regions in rat and mouse. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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