| 货号 | AF2015 |
| 别名 | GGF2 |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects human NRG1 Isoform GGF2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross‑reactivity with recombinant human (rh) NRG‑1 alpha EGF domain, rhNRG1-beta 1 extracellular domain, rhNRG1-beta 1 EGF domain, rhSMDF, and recombinant mouse NRG3 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3084 (Human); 211323 (Mouse); 112400 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant human NRG1 Isoform GGF2 Gly51-Cys248 Accession # NP_039256 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | By alternative splicing, the Neuregulin 1 gene ecodes at least 10secreted or membrane-bound proteins, all of which contain an EGF-likedomain. Neuregulin 1 isoforms bind and signal via the ErbB family ofreceptor tyrosine kinases. Isoform GGF2 contains a unique kringle-likedomain, plus Ig and EGF-like domains that are also present in multipleNeuregulin 1 isoforms. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
|