货号 | AF1919 |
别名 | C9orf2; H7365member 1; Tomoregulin-1; TR-1; Transmembrane protein with EGF-like and one follistatin-like domain; transmembrane protein with EGF-like and two follistatin-like domains 1 | 全称 | Transmembrane Protein with EFG-like and two Follistatin-like Domains |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects human TMEFF1/Tomoregulin‑1 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse TMEFF1 is observed and less than 1% cross‑reactivity with recombinant human TMEFF2 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 8577 (Human); 230157 (Mouse) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant human TMEFF1/Tomoregulin‑1 Ser40-Thr328 Accession # Q8IYR6 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | TMEFF1, also known as tomoregulin 1 is a type I transmembraneglycoprotein that contains two follistatin modules and an EGF domain inits extracellular domain, a transmembrane domain and a shortcytoplasmic tail. The extracellular domain can be released as a solubleprotein. TMEFF1 selectively regulates nodal but not activin signalingthrough direct binding to the nodal co-receptor, Cripto. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
参考文献 |
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