概述| 货号 | A-812 |
| 别名 | FLJ43224; MGC104393; MGC125896; MGC125897; NEDD-8; Neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; neural precursor cell expressed, developmentally down-regulated 8; Rub1; Ubiquitin-like protein Nedd8 |
全称 | Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8 | | 反应种属 | Human |
| 应用 | Western Blot |
| 目标/特异性 | Antibody does not cross-reactwith ubiquitn, SUMO, or ISG15 proteins. Non-functional for immunoprecipitation. |
| 使用方法 | Western Blot: Recommended dilution range forWestern blot analysis is 1:100 to 1:1000.
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| 来源 | Polyclonal Rabbit IgG |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 4738 (Human); 18002 (Mouse); 25490 (Rat) |
| 免疫原 | Full-length, highly purified human NEDD8 protein |
| 标记 | Unconjugated |
| 背景 | Theubiquitin-like protein NEDD8 is conjugated to targets by the NEDD8-specific E1 activatingenzyme (APP-B1/UBA3), the Ubc12 E2 enzyme, and the ROC1/Rbx1 RING FINGER E3ligase. NEDD8 plays a criticalregulatory role in cell proliferation and development, and modifies nearly allmembers of the cullin family. |
| 运输条件 | Dry Ice |
| 存放说明 | -80℃ |
| 参考文献 | - Gong L. et al. (1999) J. Biol. Chem. 274:12036-12042
- Hori T. et al. (1999) Oncogene 18:6829-6834
- Kamura T. et al. (1999) Genes. Dev. 13:2928-2933
- Kumar S. et al. (1993) Biophys. Biochem. Res. Comm. 195:393-399
- Morimoto M. et al. (2003) Biophys. Biochem. Res. Comm. 301:392-398
- Wada H. et al. (1999) Biophys. Biochem. Res. Comm. 275:100-105
- Whitby F. G. et al. (1998) J. Biol. Chem. 273:34983-34991
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