货号 | AF3878-SP |
别名 | Eotaxin-3-like |
反应种属 | Rat |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects rat CCL26-like/Eotaxin‑3-like in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse CCL26-like is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant rat CCL26-like/Eotaxin‑3-like Thr24-Trp94 Accession # NP_001102958 |
生物活性 | Rat |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Chemokine (CC motif) ligand 26, also known as Eotaxin 3, is a human CC chemokine ligand that binds and signals via the chemokine receptor CCR3. Rat CCL26‑like/Eotaxin 3-like is an 8.5 kDa orthologue of the human CCL26/eotaxin 3. It is a 94 amino acid (aa) residue protein with a 23 aa signal sequence and a 71 aa mature segment. It is presumed that rat CCL26-like/Eotaxin 3-like will bind CCR3 to induce eosinophil chemotaxis and transendothelial migration. Mature rat CCL26 shares 48%, 63%, and 48% aa sequence identity with the human, mouse and canine CCL26/Eotaxin 3, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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