| 货号 | AF3465-SP |
| 别名 | LU103; Pneumo secretory protein 1; PnSP-1; PNSP1secretoglobin family 3A member 2; SCGB3A2; secretoglobin, family 3A, member 2; UGRP1pnSP-1; Uteroglobin-related protein 1 | 全称 | Uteroglobin-related Protein 1 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse UGRP1/SCGB3A2 isoforms C and A in direct ELISAs and Western blots. It is also expected to recognize isoform B in direct ELISAs and Western blots. In Western blots, approximately 15% cross-reactivity with recombinant human UGRP1 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 117156 (Human); 117158 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse UGRP1/SCGB3A2 isoform C Leu22-Leu139 Accession # Q920H1 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | UGRP-1, also known as secretoglobin family 3A member 2 (SCGB3A2) andHIN-2, is a secreted homodimeric protein that is highly expressed inepithelial cells of the airway. By alternative splicing events, threeisoforms (A, B, C) that differ in their C-terminal regions, exist.UGRP-1 has been shown to bind MARCO (macrophage scavenger receptor withcollagenous structure), which is expressed by alveolar macrophages.UGRP1 has been suggested to play a role in lung inflammation. Maturemouse UGRP1 isoform A shares 86% and 81% amino acid sequence identitywith rat and human mature UGRP1, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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