| 货号 | AF3376-SP |
| 别名 | CLAXLLT-1; CLEC2D; C-type lectin domain family 2 member D; C-type lectin domain family 2, member D; C-type lectin related f; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT1; LLT1Osteoclast inhibitory lectin; OCILmember D | 全称 | Osteoclast Inhibitory Lectin |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse OCIL/CLEC2d in direct ELISAs and Western blots. In Western blots, approximately 35% cross-reactivity with recombinant mouse OCILRP2 is observed and less than 2% cross-reactivity with recombinant human OCIL is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 29121 (Human); 93694 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse OCIL/CLEC2d Ala65-Ser207 Accession # Q91V08 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Mouse OCIL, also known as C-type lectin-related b (Clrb), is a type IItransmembrane protein belonging to the natural killer (NK) cellreceptor group of the C-type lectin superfamily. It is found onhematopoietic cells, osteoclasts and chondrocytes. OCIL preferentiallybinds high molecular weight, sulfated glycosaminoglycans and is aligand for the mouse NK R-PIB/D receptor. OCIL blocks osteoclastdifferentiation. Engagement of OCIL with NK R-PIB/D on NK cellsinhibits NK cell functions. The extracellular domain of mouse OCILshares 49% and 71% amino acid sequence identity with rat and humanOCIL, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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