| 货号 | AF3370-SP |
| 别名 | CLEC2i; CLRG | 全称 | Osteoclast Inhibitory Lectin Related Protein 2 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse OCILRP2/CLEC2i in direct ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse OCIL is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 93675 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse OCILRP2/CLEC2i Thr77-Val217 Accession # Q9WVF9 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | OCILRP2, also known as CLRG (C-type lectin related g) and CLEC2i(C-type lectin domain family 2, member i), is a type II transmembraneprotein whose gene has been mapped to the natural killer gene complex(NKC) on mouse chromosome 6. By alternative splicing, multiple isoformsexist. OCIL RP2 is expressed on osteoclasts, chondrocytes and lymphoidcell types. It is a ligand for NKrp1f (KLRB1f), another NK receptor onthe NKC. OCILRP2 inhibits osteoclast formation and can affect NK cellfunctions. The extracellular domain of mouse OCILRP2 shares 79% and 74%amino acid sequence identity with that of mouse OCILRP1 and OCIL,respectively. A human OCILRP2 ortholog has not been identified. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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