Human Transglutaminase 7/TGM7 Affinity Purified PAb (25 UG)
货号：
AF5426-SP 基本售价：
1407.8 元 规格：
-
产品信息
概述| 货号 | AF5426-SP |
| 别名 | protein-glutamine gamma-glutamyltransferase Z; TG(Z); TGase Z; TGase-7; TGM7; TGMZ; TGMZEC 2.3.2.13; TGZ; transglutaminase 7; Transglutaminase Z; transglutaminase-7 |
| 反应种属 | Human |
| 应用 | Western Blot(1 µg/mL)
|
| 目标/特异性 | Detects human Transglutaminase 7/TGM7 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross‑reactivity with recombinant human (rh) Transglutaminase 3 is observed, and less than 2% cross-reactivity with rhTransglutaminase 2, rhTransglutaminase 4, and recombinant mouse Transglutaminase 2 is observed. |
| 使用方法 | Western Blot: 1 µg/mL
|
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 116179 (Human); 640543 (Mouse); 691932 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Transglutaminase 7/TGM7 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Transglutaminase 7 (TG7), encoded by the TGM7 gene, is also known as protein-glutamine-g-glutamyltransferase Z (Tgase Z). It belongs to the family of transglutaminases that catalyze the posttranslational modification of proteins via calcium dependent cross-linking reactions. TG7 is ubiquitously expressed in humans. Members of the TGM family have been implicated in a variety of human diseases including neurodegenerative diseases, celiac disease, lamellar ichthyosis, bleeding disorders, cataract formation, atherosclerosis, and others. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Extracellular Matrix Molecules
- Inflammatory Mediators
- Parkinsons Disease Related Molecules
|
参考图片Detection of Human Transglutaminase 7/TGM7 by Western Blot.Western blot shows lysates of human thyroid tissue. PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human Transglutaminase 7/TGM7 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF5426) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for Transglutaminase 7/TGM7 at approximately XXX kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 8. |
