| 货号 | AF4647-SP |
| 别名 | aminopeptidase O; AOPEP; APO; AP-OFLJ55832; C90RF3; C9orf3; chromosome 9 open reading frame 3; EC 3.4.11.-; FLJ14675; FLJ40923; ONPEP |
| 反应种属 | Human |
| 应用 | Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL) Immunoprecipitation(25 µg/mL) |
| 目标/特异性 | Detects human Aminopeptidase O/ONPEP in direct ELISAs and Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL Immunoprecipitation: 25 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 84909 (Human); 72061 (Mouse); 290963 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Aminopeptidase O/ONPEP isoform 1 Met1-Phe819 Accession # Q8N6M6 |
| 生物活性 | Human |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Aminopeptidase O (AP-O; also C9orf3) is a 93 kDa (predicted), intracellular member of the M1 metalloprotease family of enzymes. It is expressed in heart, testis and pancreas where it cleaves N-terminal Arg and Asn residues. Human AP-O is 819 amino acids in length. Aminopeptidase O contains one catalytic domain (aa 167 - 589) with a zinc-binding site (His479 - His483) and a C-terminal ARM region (aa 706 - 819). At least three additional isoforms of Aminopeptidase O exist. Full-length human AP-O is 76% aa identical to mouse AP-O. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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