Human alpha 1-Acid Glycoprotein Affinity Purified PAb (25 UG)
货号:
AF3694-SP 基本售价:
1407.8 元 规格:
-
产品信息
概述货号 | AF3694-SP |
别名 | AGP 1; AGP; AGP1; AGP1alpha-1-acid glycoprotein 1; AGPA; AGP-A; OMD 1; ORM; ORM1; orosomucoid 1; Orosomucoid; orosomucoid-1 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL)
|
目标/特异性 | Detects human alpha 1-Acid Glycoprotein in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mose alpha 1-Acid Glycoprotein is observed. |
使用方法 | Western Blot: 0.1 µg/mL
|
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 | |
性能供应商 | R&D Systems |
Entrez Gene IDs | 5004 (Human); 18405 (Mouse); 24614 (Rat) |
应用文献 |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Astrocytic orosomucoid-2 modulates microglial activation and neuroinflammation Authors: M Jo, JH Kim, G Song, M Seo, E Mi Hwang, K Suk J. Neurosci, 2017;0(0):. Species: Mouse Sample Type: Cell Lysates Application: WB |
纯化方式 | Antigen Affinity-purified |
免疫原 | Human plasma-derived alpha 1-Acid Glycoprotein |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | alpha 1-acid Glycoprotein, also known as orosomucoid-1, is a positiveacute-phase reactant that is produced by the liver and secreted inplasma. Plasma alpha 1-acid concentration increases in response toinflammation and infection. alpha 1-acid glycoprotein belongs to thelipocalin family and binds numerous basic and neutral lipophilic drugsand steroid hormones. It is a 183 amino acid protein with 5 N-linkedglycans that comprises 45% of the 43 kDa mass of the protein. The humanand mouse protein share 43% amino acid sequence identity. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - Acute Phase Proteins
- ICC / IHC Images: alpha 1-Acid Glycoprotein
- Inflammatory Mediators
|
参考图片Detection of Human alpha 1‑Acid Glycoprotein by Western Blot. Western blot shows human plasma. PVDF membrane was probed with 0.1 µg/mL of Goat Anti-Human alpha 1‑Acid Glycoprotein Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3694) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for alpha 1‑Acid Glycoprotein at approximately 45-50 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1. |