货号 | AF3560-SP |
别名 | CN2; CN2cytosolic non-specific dipeptidase; CNDP dipeptidase 2 (metallopeptidase M20 family); CNDP dipeptidase 2; CNDP2; CPGL; CPGLcytosolic nonspecific dipeptidase; FLJ10830; HsT2298; PEPA; PEPAEC 3.4.13.18; Peptidase AGlutamate carboxypeptidase-like protein 1 |
反应种属 | Human |
应用 | Western Blot(0.1 µg/mL) Immunoprecipitation(25 µg/mL) |
目标/特异性 | Detects human Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human CPGL-2 is observed. |
使用方法 | Western Blot: 0.1 µg/mL Immunoprecipitation: 25 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 55748 (Human) |
纯化方式 | Antigen Affinity-purified |
免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Cytosol Nonspecific Dipeptidase (CNDP2)/CPGL Ala2-Asp475 Accession # Q96KP4 |
生物活性 | Human |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The human CNDP2 gene encodes cytosol non-specific dipeptidase, a member of the M20 family of metalloproteases (1, 2). Also known as glutamate carboxypeptidase-like protein 1 (CPGL), tissue carnosinase or peptidase A, CNDP2 is ubiquitously expressed throughout human tissues. Unlike CNDP1, CNDP2 has broad substrate specificity for dipeptides with free amino and carboxyl groups. The purified recombinant human CNDP2 migrates as three bands in SDS-PAGE under reducing conditions that correspond to the full length protein (54 kDa), the N-terminal fragment (33 kDa) and the C-terminal fragment (22 kDa). The initiator Met1 may be removed and Ala2 may be acetylated based on Accession # Q96KP4. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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