货号 | AF573-SP |
别名 | IL-1 R6; IL1RL2; IL-1RL2 | 全称 | Interleukin 1 Receptor-like 2 |
反应种属 | Rat |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects rat IL‑1 Rrp2/IL‑1 R6 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross‑reactivity with recombinant human (rh) IL‑1 R6 is observed and less than 5% cross‑reactivity with rhIL-18 R beta, rhIL-1 RI, and rhIL‑1 RII is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 8808 (Human); 107527 (Mouse); 171106 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant rat IL‑1 Rrp2/IL‑1 R6 Gly22-Tyr340 Accession # Q62929 |
内毒素水平 | <0.10 EU per 1 μg of the antibody by the LAL method. |
生物活性 | Rat |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. IL-1 Rrp2, also known as IL-1 R6, is a transmembrane protein belonging to the IL-1 receptor family. It is a ligand binding subunit that associates with IL-1 RAcP to form a functional receptor complex for IL-1F6, IL-1F8, and IL-1F9. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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