Mouse Endostatin Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Mouse Endostatin Affinity Purified Polyclonal Ab (25 UG)

货号： AF570-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF570-SP
别名	antiangiogenic agent; COL18A1; collagen alpha-1(XVIII) chain; collagen, type XVIII, alpha 1; FLJ27325; FLJ34914; human type XVIII collagen10endostatin; KNO; KNO1MGC74745; Knobloch syndrome, type 1; KS; multi-functional protein MFP
反应种属	Mouse
应用	Western Blot(0.1 µg/mL) Immunohistochemistry(5-15 µg/mL)
目标/特异性	Detects mouse Endostatin in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human Endostatin is observed.
使用方法	Western Blot: 0.1 µg/mL Immunohistochemistry: 5-15 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	80781 (Human); 12822 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Type IV collagen stimulates pancreatic cancer cell proliferation, migration, and inhibits apoptosis through an autocrine loop. Authors: Ohlund D, Franklin O, Lundberg E, Lundin C, Sund M BMC Cancer, 2013;13(0):154. Species: Human Sample Type: tissue Application: IHC Frozen Host-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endostatin production. Authors: Fukuda H, Mochizuki S, Abe H, Okano HJ, Hara-Miyauchi C, Okano H, Yamaguchi N, Nakayama M, DArmiento J, Okada Y Br. J. Cancer, 2011;105(10):1615-24. Species: Mouse Sample Type: Tissue Homogenates Application: WB Cationic liposome coupled endostatin gene for treatment of peritoneal colon cancer. Authors: Lan KL, Ou-Yang F, Yen SH, Shih HL, Lan KH Clin. Exp. Metastasis, 2010;27(5):307-18. Species: Mouse Sample Type: Serum Application: ELISA Development Endostatin peptide, an inhibitor of angiogenesis, prevents the progression of peritoneal sclerosis in a mouse experimental model. Authors: Tanabe K, Maeshima Y, Ichinose K, Kitayama H, Takazawa Y, Hirokoshi K, Kinomura M, Sugiyama H, Makino H Kidney Int., 2007;71(3):227-38. Species: Mouse Sample Type: Whole Tissue Application: IHC Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells. Authors: Lederle W, Stark HJ, Skobe M, Fusenig NE, Mueller MM Am. J. Pathol., 2006;169(5):1767-83. Species: Mouse Sample Type: Whole Tissue Application: IHC
纯化方式	Antigen Affinity-purified
免疫原	S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Endostatin His1105-Lys1288 Accession # AAA19787
内毒素水平	<0.20 EU per 1 μg of the antibody by the LAL method.
生物活性	Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	Endostatin is a fragment of collagen XVIII and functions as an angiogenesis antagonist.
运输条件	Blue Ice
存放说明	4℃
参考文献	Extracellular Matrix and Related Molecules Extracellular Matrix Molecules ICC / IHC Images: Endostatin Renal Markers

参考图片

Endostatin in Mouse Intestine. Endostatin was detected in perfusion fixed frozen sections of mouse intestine using Goat Anti-Mouse Endostatin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF570) at 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Specific staining was localized to lacteals. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.