| 货号 | AF553-SP |
| 别名 | CD125 antigen; CD125; CDw125CD125; HSIL5R3; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5RA; IL-5R-alpha; interleukin 5 receptor type 3; interleukin 5 receptor, alpha; interleukin-5 receptor alpha chain; interleukin-5 receptor alpha subunit; interleukin-5 receptor subunit alpha; MGC26560 | 全称 | Interleukin 5 Receptor alpha |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse IL‑5 R alpha /CD125 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross‑reactivity with recombinant human (rh) IL‑5 R alpha is observed and less than 1% cross‑reactivity with recombinant mouse (rm) IL-4 R, rhIL-9 R, rhIL-13 R alpha 1, and rhIL-13 R alpha 2 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3568 (Human); 16192 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Defective eosinophil hematopoiesis ex vivo in inbred Rocky Mountain White (IRW) mice. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse IL‑5 R alpha /CD125 Asp18-His339 Accession # P21183 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | As is the case with many other cytokines, the functional high-affinity receptor for IL-5 is a complex consisting of a ligand binding subunit (alpha chain) and a second subunit (beta chain) that can modulate the ligand binding affinity of the receptor complex. In the case of IL-5, the beta subunit is shared with the high affinity receptor complexes for IL-3 and GM-CSF and is called the common beta chain. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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