Mouse Serpin I1 Affinity Purified Polyclonal Ab (25 UG)
货号：
AF5054-SP 基本售价：
1378.1 元 规格：
-
产品信息
概述| 货号 | AF5054-SP |
| 别名 | DKFZp781N13156; Neuroserpin; Peptidase inhibitor 12; PI12; PI-12; PI12Serpin I1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL)
|
| 目标/特异性 | Detects mouse Serpin I1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human (rh) Serpin I1 is observed and less than 5% cross‑reactivity with rhSerpin I2is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL
|
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5274 (Human); 20713 (Mouse); 116459 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse Serpin I1 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Interactive Pathway: Blood Coagulation Signaling Pathways
- Serine Proteases and Regulators
|
