货号 | AF4464-SP |
别名 | ATPDase; CD39 antigen-like 3; CD39L3; CD39L3EC 3.6.1.5; CD39-like 3; EC 3.6.1; Ecto-apyrase 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPase 3; Ecto-ATPDase 3; ectonucleoside triphosphate diphosphohydrolase 3; ENTPD3; FLJ93839; HB6; HB6NTPDase 3; NTPDase-3 | 全称 | Ecto-Nucleoside Triphosphate Diphosphohydrolase 3 |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) Immunoprecipitation(25 µg/mL) |
目标/特异性 | Detects mouse CD39L3/ENTPD3 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross‑reactivity with recombinant human CD39L3 is observed. |
使用方法 | Western Blot: 0.1 µg/mL Immunoprecipitation: 25 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 956 (Human); 215446 (Mouse); 316077 (Rat) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Expression and distribution of ectonucleotidases in mouse urinary bladder. | |
纯化方式 | Antigen Affinity-purified |
免疫原 | Chinese hamster ovary cell line CHO-derived recombinant mouse CD39L3/ENTPD3 Gln44-Pro485 Accession # AAH79871 |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | CD39L3 (CD39-like 3; also HB6 and ectonucleoside triphosphate diphosphohydrolase-3/eNTPDase 3) is an 80 kDa, class I member of the GDA1/CD39 NTPase family of transmembrane (TM) enzymes. It is a cell surface glycoprotein that hydrolyses both extracellular ATP and ADP. Thus, it controls ATP activation of P2X ion channel purinoreceptors. Mouse CD39L3 is 529 amino acids (aa) in length. It contains two TM segments plus an N- and C-terminal cytoplasmic region. Based on human CD39L3, the mouse extracellular domain (ECD) will contain aa 44 - 485. Within the ECD, mouse CD39L3 shares 82% and 94% aa identity with human and rat CD39L3 ECD, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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