| 货号 | AF4156-SP |
| 别名 | B Lymphocyte Activator Macrophage Expressed; BCM-Like Membrane Protein; B-Lymphocyte Activator Macrophage Expressed; CD353 Antigen; CD353; SBBI42; SLAM Family Member 8; SLAMF8 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse BLAME/SLAMF8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant human BLAME is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 56833 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse BLAME/SLAMF8 Val21-Asp231 Accession # Q9D3G2 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | BLAME (B-lymphocyte activator macrophage expressed), also known as SLAM family member 8, is a type I transmembrane protein that belongs to the CD2 subset of the Ig superfamily cell receptors. The 258 amino acid (aa) mature mouse BLAME contains a 211 aa extracellular domain (ECD) with an Ig V- and a C2-like domain, and a 26 aa cytoplasmic tail that lacks signaling motifs. BLAME is expressed by activated monocytes and dendritic cells. Although the function of BLAME is not known, it is likely involved in homotypic binding or heterotypic interactions with other CD2 subset members. Over the ECD region used as immunogen, mouse BLAME shares 95% and 78% aa identity with rat and human BLAME, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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