货号 | AF3906-SP |
别名 | bone- and odontoblast-expressed gene 1; Bono1; FKSG28; FKSG40; FLJ24094; IGFBP-related protein 10; IGFBP-rP10; KAZALD1; Kazal-type serine peptidase inhibitor domain 1; Kazal-type serine protease inhibitor domain 1; kazal-type serine protease inhibitor domain-containing protein 1; novel kazal-type serine protease inhibitor domain and immunoglobulin domain containing protein; UNQ2945/PRO21184 | 全称 | Insulin-like Growth Factor Binding Protein Related Protein-10 |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse IGFBP‑rP10 in direct ELISAs and Western blots. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 81621 (Human); 107250 (Mouse); 293997 (Rat) |
纯化方式 | Antigen Affinity-purified |
免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse IGFBP‑rP10 Arg38-Tyr313 Accession # NP_849260 |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | IGFBP-rP10, also known as Kazal-type serine protease inhibitor domain-containing protein 1 and bone and odontoblast-expressed protein 1, belongs to the IFGBP superfamily. It is a 276 amino acid (aa) residue, 36 kDa secreted protein that contains an N-terminal IGFBP domain, a Kazal-type serine protease inhibitor region, a C2-type Ig-like domain and a C-terminal poly-glu segment. An alternate variant with a 16 aa substitution for the C-terminal 33 residues has also been reported. IGFBP‑rP10 is expressed in multiple tissues including osteoblasts/odontoblasts and is up-regulated during osteoblast differentiation and bone regeneration. Mouse mature IGFBP-rP10 shares 96% and 87% aa sequence identity with rat and human IGFBP-rP10, respectively. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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