| 货号 | AF3779-SP |
| 别名 | Cerebral protein 2; Egr5; KIAA1994; MGC17597; Regulatory protein TSC-22; RP11-269C23.2; TGFB1I4; TGFB-stimulated clone 22 homolog; transforming growth factor beta 1 induced transcript 4; Transforming growth factor beta-1-induced transcript 4 protein; transforming growth factor beta-stimulated protein TSC-22; TSC22 domain family 1; TSC22 domain family protein 1; TSC22 domain family, member 1; TSC22D1; TSC22DKFZp686O19206 | 全称 | TSC22 Domain Family, Member 1 |
| 反应种属 | Mouse/Rat |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse and rat TSC22 in direct ELISAs and Western blots. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 8848 (Human); 21807 (Mouse) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse TSC22 Met1-Ala143 Accession # P62500.2 |
| 生物活性 | Mouse, Rat |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Mouse TSC22 is an intracellular 18 kDa (143 aa) protein that belongs tothe TSC22/Dip/Bun family of leucine zipper transcription regulators.Family members share a highly conserved central TSC box-leucine zipperdomain that is important for dimerization and distinct N- and C-terminithat participate in transcriptional regulation. TSC22 can homodimerizeor heterodimerize with other family members to function as a repressivetranscription factor. Mouse TSC22 shares 100% and 98.5% amino acidsequence homology with rat and human TSC22, respectively. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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