Mouse BAMBI/NMA Affinity Purified Polyclonal Ab (25 UG)【科瑞奥博】

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Mouse BAMBI/NMA Affinity Purified Polyclonal Ab (25 UG)

货号： AF2387-SP 基本售价： 1378.1 元规格： -

产品信息

概述
货号	AF2387-SP
别名	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis); BMP and activin membrane-bound inhibitor homolog; NMA; NMANon-metastatic gene A protein; Putative transmembrane protein NMA
全称	BMP and Activin Membrane-bound Inhibitor
反应种属	Mouse
应用	Western Blot(1 µg/mL)
目标/特异性	Detects mouse BAMBI/NMA in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant human BAMBI is observed.
使用方法	Western Blot: 1 µg/mL
来源	Reconstitute at 0.2 mg/mL in sterile PBS.
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	25805 (Human); 68010 (Mouse)
应用文献
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation. Authors: Tramullas M, Lantero A, Diaz A, Morchon N, Merino D, Villar A, Buscher D, Merino R, Hurle JM, Izpisua-Belmonte JC, Hurle MA J. Neurosci., 2010;30(4):1502-11. Species: Mouse Sample Type: Whole Tissue Application: IHC Paraffin-embedded BAMBI is expressed in endothelial cells and is regulated by lysosomal/autolysosomal degradation. Authors: Xavier S, Gilbert V, Rastaldi MP, Krick S, Kollins D, Reddy A, Bottinger E, Cohen CD, Schlondorff D PLoS ONE, 2010;5(9):e12995. Species: Mouse Sample Type: Tissue Lysate Application: WB TLR4 enhances TGF-beta signaling and hepatic fibrosis. Authors: Seki E, De Minicis S, Osterreicher CH, Kluwe J, Osawa Y, Brenner DA, Schwabe RF Nat. Med., 2007;13(11):1324-32. Species: Mouse Sample Type: Cell Lysates Application: WB
纯化方式	Antigen Affinity-purified
免疫原	Mouse myeloma cell line NS0-derived recombinant mouse BAMBI/NMA Ile28-Thr143 Accession # Q9D0L6
生物活性	Mouse
标记	Unconjugated
溶解方法	Reconstitute at 0.2 mg/mL in sterile PBS.
背景	BAMBI/NMA is a type I transmembrane protein that shares sequence homology with the TGF-beta type I receptor family protein but has a short cytoplasmic region that lacks the kinase domain. It functions as a membrane-bound decoy receptor by competing with type I receptors to form a heterodimer with type II receptors. Mouse BAMBI/NMA share approximately 93% amino acid sequence homology with human BAMBI/NMA.
运输条件	Blue Ice
存放说明	4℃
参考文献	BMP Family TGF-beta Family TGF-beta Superfamily TGF-beta Superfamily Modulators

参考图片

Detection of Mouse BAMBI/NMA by Western Blot. Western blot shows lysates of mouse liver tissue. PVDF Membrane was probed with 1 µg/mL of Goat Anti-Mouse BAMBI/NMA Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2387) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for BAMBI/NMA at approximately 32 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.