| 货号 | AF2220-SP |
| 别名 | CD33 antigen (gp67); CD33 antigen; CD33 molecule; CD33; FLJ00391; gp67; myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; Sialic acid-binding Ig-like lectin 3; SIGLEC-3; SIGLEC3gp67 | 全称 | Sialic Acid Binding Ig-like Lectin 3 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse Siglec-3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) Siglec-7 and rhSiglec-9 and less than 5% cross-reactivity with recombinant mouse (rm) Siglec-F, rmSiglec-2, rhSiglec‑3, rhSiglec-5, and rhSiglec-10 is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 945 (Human); 12489 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Siglec-3/CD33 Gln17-Val244 Accession # Q63994 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type)cell-surface lectins that recognize sialic acid within specific glycanstructures. Mouse Siglec-3, also known as CD33 and GP67, is expressedprimarily on myeloid precursors in the bone marrow and on granulocytesin peripheral blood. Two isoforms have been reported for mouse Siglec-3that display distinct cytoplasmic domains resulting from differentialmRNA splicing. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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