| 货号 | AF1905-SP |
| 别名 | DKFZp779H1622; Histidine-proline-rich glycoprotein; histidine-rich glycoprotein; HPRGHRGP; HRG | 全称 | Histidine-rich Glycoprotein Precusor |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) |
| 目标/特异性 | Detects mouse HPRG in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross‑reactivity with recombinant human HPRG is observed and less than 2% cross-reactivity wth recombinant mouse (rm) Cystatin A, rmCystatin B, rmCystatin C, and rmCystatin E/M is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 3273 (Human) |
| 应用文献 | |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Differential proteomics analysis of the surface heterogeneity of dextran iron oxide nanoparticles and the implications for their in vivo clearance. | |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse HPRG Leu19-Lys525 Accession # BAB33094 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | HPRG (Histidine-Proline-rich Glycoprotein) is a novel member of the Cystatin superfamily of cysteine proteinase inhibitors. It is a circulating glycoprotein, 67kDa in size with multiple modules. N-terminally, there are two Cystatin-like domains that interact with the immune system. C-terminally, there is one His-Pro-rich domain that is flanked by two Pro-rich segments. The Pro-rich regions bind Plasminogen while the His-Pro module binds heparan under low pH conditions. It shows anti-angiogenic and anti-fibrinolytic activity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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