货号 | AF1657-SP |
别名 | ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; lithostathine-1-alpha; Pancreatic stone protein; pancreatic stone protein, secretory; Pancreatic thread protein; protein-X; PSPregenerating islet-derived 1 alpha (pancreatic stone protein, pancreatic threadprotein); PSPS1REG-1-alpha; PSPSMGC12447; PTPP19; regenerating islet-derived 1 alpha; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; REGlithostathine 1 alpha | 全称 | Regenerating Islet-derived 1 |
反应种属 | Mouse |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects mouse Reg1 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse (rm) Reg2 is observed and less than 5% cross-reactivity with rmReg3A, recombinant human (rh) Reg1B, rhReg4, recombinant rat (rr) Reg3 and rrReg2 is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
Entrez Gene IDs | 19692 (Mouse) |
应用文献 | |
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation. | |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant mouse Reg1 Gln22-Gly165 Accession # P43137 |
生物活性 | Mouse |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Reg1, also known as pancreatic thread protein (PTP), pancreatic stone protein (PSP) and lithostathine, is the founding member of the Reg family of proteins, which are secreted proteins with a C-type lectin domain. Reg1 is expressed during islet regeneration. Reg1 functions in an autocrine/paracrine fashion via a cell surface Reg receptor that mediates a growth signal for beta -cell regeneration (1). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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