货号 | AF698-SP |
别名 | MIPIII; MIP-III | 全称 | Macrophage Inflammatory Protein III |
应用 | Western Blot(0.1 µg/mL) |
目标/特异性 | Detects viral MIP‑III in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with _______________ is observed. |
使用方法 | Western Blot: 0.1 µg/mL |
来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
产品组分 |
供应商 | R&D Systems |
纯化方式 | Antigen Affinity-purified |
免疫原 | E. coli-derived recombinant human herpes virus-8 MIP-III Ser27-Pro114 Accession # P88968 |
生物活性 | Viral |
标记 | Unconjugated |
溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
背景 | Human herpesvirus-8 (HHV-8)/Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes a variety of immunomodulatory proteins which were apparently pirated from cellular genes by the virus. Three chemokine-like proteins, vMIP-I, vMIP-II and vMIP-III have been found within the HHV-8 genome. Viral MIP-II cDNA encodes a 94 amino acid (aa) residue precursor protein with a 23 aa residue signal peptide that is cleaved to yield a 71 aa residue mature protein. Among human chemokines, vMIP-II is most closely related to MIP-1 alpha, sharing approximately 41% amino acid sequence identity. At the amino acid sequence level, vMIP-I and vMIP-II also share 48% identity. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 |
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